Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Abcc4tm1Jsch
Name:	ATP-binding cassette, sub-family C member 4; targeted mutation 1, John D Schuetz
MGI ID:	MGI:3047326
Synonyms:	Mrp4-
Gene:	Abcc4  Location: Chr14:118720104-118943631 bp, - strand  Genetic Position: Chr14, 62.24 cM
Alliance:	Abcc4tm1Jsch page

Germline Transmission:	Earliest citation of germline transmission: J:90692
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance gene replaced exon 27. Immunoblot analysis of membrane fractions showed complete loss of protein in mutants. (J:92788)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abcc4 Mutation:	151 strains or lines available

Original:	J:90692 Assem M, et al., Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. J Biol Chem. 2004 May 21;279(21):22250-7
All:	20 reference(s)