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Zdhhc8tm1Kara
Targeted Allele Detail
Summary
Symbol: Zdhhc8tm1Kara
Name: zinc finger, DHHC domain containing 8; targeted mutation 1, Maria Karayiorgou
MGI ID: MGI:3047084
Synonyms: Zdhhc8-
Gene: Zdhhc8  Location: Chr16:18038617-18053000 bp, - strand  Genetic Position: Chr16, 11.29 cM
Alliance: Zdhhc8tm1Kara page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:91131
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA floxed pACN cassette that includes a neo replaced exons 2-11. Southern blot showed successful recombination and brain RT-PCR indicated lack of transcript in mutants. (J:91131)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zdhhc8 Mutation:  25 strains or lines available
References
Original:  J:91131 Mukai J, et al., Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia. Nat Genet. 2004 Jul;36(7):725-31
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory