Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cdhr1tm1Nat
Name:	cadherin-related family member 1; targeted mutation 1, Jeremy Nathans
MGI ID:	MGI:3046299
Synonyms:	prCAD-
Gene:	Cdhr1  Location: Chr14:36799814-36820304 bp, - strand  Genetic Position: Chr14, 21.29 cM
Alliance:	Cdhr1tm1Nat page

Germline Transmission:	Earliest citation of germline transmission: J:73286
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin selection cassette replaced exons 10-17, which encode the C-terminal two thirds of the protein. Northern blot and immunohistochemical analysis confirmed the absence of encoded transcript and protein, respectively. (J:73286)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cdhr1 Mutation:	54 strains or lines available

Original:	J:73286 Rattner A, et al., A photoreceptor-specific cadherin is essential for the structural integrity of the outer segment and for photoreceptor survival. Neuron. 2001 Dec 6;32(5):775-86
All:	5 reference(s)