Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gfra1tm1Bjh
Name:	glial cell line derived neurotrophic factor family receptor alpha 1; targeted mutation 1, B J Hoffer
MGI ID:	MGI:3045109
Synonyms:	GFRalpha1 -
Gene:	Gfra1  Location: Chr19:58224036-58444341 bp, - strand  Genetic Position: Chr19, 54.18 cM, cytoband D2-D3
Alliance:	Gfra1tm1Bjh page

Germline Transmission:	Earliest citation of germline transmission: J:60458
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     The first exons were replaced with a PGK-neomycin resistance cassette in reverse orientation. (J:60458)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gfra1 Mutation:	31 strains or lines available

Original:	J:60458 Tomac AC, et al., Glial cell line-derived neurotrophic factor receptor alpha1 availability regulates glial cell line-derived neurotrophic factor signaling: evidence from mice carrying one or two mutated alleles. Neuroscience. 2000;95(4):1011-23
All:	5 reference(s)