Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Il1rl1tm1Brl
Name:	interleukin 1 receptor-like 1; targeted mutation 1, RCC, Ltd
MGI ID:	MGI:3043989
Synonyms:	TgH(GS-T1)Brl
Gene:	Il1rl1  Location: Chr1:40468730-40504575 bp, + strand  Genetic Position: Chr1, 19.19 cM
Alliance:	Il1rl1tm1Brl page

Germline Transmission:	Earliest citation of germline transmission: J:63507
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: 4.8 kb of the endogenous gene, including part of exon 2 and all of exons 3 to 6, were deleted and replaced by the lacZ gene followed by a neomycin resistance gene. Expression of the endogenous gene was abolished. Expression of beta-galactosidase was not reported. (J:63507)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Il1rl1 Mutation:	56 strains or lines available

Original:	J:63507 Senn KA, et al., T1-deficient and T1-Fc-transgenic mice develop a normal protective Th2-type immune response following infection with Nippostrongylus brasiliensis. Eur J Immunol. 2000 Jul;30(7):1929-38
All:	4 reference(s)