Summary | Mutation origin | Mutation description | Expression | Find Mice (IMSR) | References

Symbol:	Htttm3Detl
Name:	huntingtin; targeted mutation 3, Peter J Detloff
MGI ID:	MGI:3043022
Gene:	Htt  Location: Chr5:34919084-35069878 bp, + strand  Genetic Position: Chr5, 17.92 cM
Alliance:	Htttm3Detl page

Germline Transmission:	Earliest citation of germline transmission: J:67074
Parent Cell Line:	HM-1 (ES Cell)
Strain of Origin:	129P2/OlaHsd-Hprt1b-m3

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Exon 1 and the promoter were replaced with an HPRT minigene. (J:67074)

In Mice Carrying this Mutation:

8 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Htt Mutation:	179 strains or lines available

Original:	J:67074 Lin CH, et al., Neurological abnormalities in a knock-in mouse model of Huntington's disease. Hum Mol Genet. 2001 Jan 15;10(2):137-44
All:	2 reference(s)