Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tfap2ctm1.1Hsc
Name:	transcription factor AP-2, gamma; targeted mutation 1.1, Hubert Schorle
MGI ID:	MGI:3040993
Gene:	Tfap2c  Location: Chr2:172391513-172400542 bp, + strand  Genetic Position: Chr2, 94.87 cM, cytoband H3-H4
Alliance:	Tfap2ctm1.1Hsc page

Germline Transmission:	Earliest citation of germline transmission: J:78934
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: A single loxP site was inserted 5' to exon 5 and a loxP flanked neomycin and thymidine kinase selection cassette was inserted 3' to exon 5. Exon 5 and the neomycin and thymidine kinase selection cassette were removed in ES cells by Cre mediated recombination prior to the production of chimeric mice, resulting in the null allele. (J:78934)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tfap2c Mutation:	28 strains or lines available

Original:	J:78934 Werling U, et al., Transcription factor gene AP-2 gamma essential for early murine development. Mol Cell Biol. 2002 May;22(9):3149-56
All:	4 reference(s)