Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Serpinb5tm1Zha
Name:	serine (or cysteine) peptidase inhibitor, clade B, member 5; targeted mutation 1, Ming Zhang
MGI ID:	MGI:3040188
Synonyms:	Mp-
Gene:	Serpinb5  Location: Chr1:106788905-106811078 bp, + strand  Genetic Position: Chr1, 50.34 cM
Alliance:	Serpinb5tm1Zha page

Germline Transmission:	Earliest citation of germline transmission: J:89192
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 7, encoding the reactive center loop, part of intron 6 and the entire 3' UTR were replaced with a neomycin resistance gene by homologous recombination. There was no transcript present in RT-PCR analysis of mutant embryoid bodies. (J:89192)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Serpinb5 Mutation:	34 strains or lines available

Original:	J:89192 Gao F, et al., Maspin plays an essential role in early embryonic development. Development. 2004 Apr;131(7):1479-89
All:	3 reference(s)