Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Psme3tm1Tchi
Name:	proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki); targeted mutation 1, Tomoki Chiba
MGI ID:	MGI:3038739
Synonyms:	PA28gamma-
Gene:	Psme3  Location: Chr11:101207039-101214363 bp, + strand  Genetic Position: Chr11, 64.67 cM
Alliance:	Psme3tm1Tchi page

Germline Transmission:	Earliest citation of germline transmission: J:89182
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin cassette replaced approximately 3kb including exons 2 - 8. Northern and Western blot analysis confirmed the absence of RNA and protein in homozygotes (J:89182)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Psme3 Mutation:	17 strains or lines available

Original:	J:89182 Murata S, et al., Growth retardation in mice lacking the proteasome activator PA28gamma. J Biol Chem. 1999 Dec 31;274(53):38211-5
All:	5 reference(s)