Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cd93tm1Mbo
Name:	CD93 antigen; targeted mutation 1, Marina Botto
MGI ID:	MGI:3038703
Synonyms:	CD93-
Gene:	Cd93  Location: Chr2:148278571-148285455 bp, - strand  Genetic Position: Chr2, 73.48 cM
Alliance:	Cd93tm1Mbo page

Germline Transmission:	Earliest citation of germline transmission: J:88610
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin cassette replaced an 1128 bp fragment in exon 1. Absence of mRNA and protein expression was confirmed by RT-PCR and FACS analysis on peritoneal macrophages and immature B cells respectively. (J:88610)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd93 Mutation:	20 strains or lines available

Original:	J:88610 Norsworthy PJ, et al., Murine CD93 (C1qRp) contributes to the removal of apoptotic cells in vivo but is not required for C1q-mediated enhancement of phagocytosis. J Immunol. 2004 Mar 15;172(6):3406-14
All:	13 reference(s)