Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ccr10tm1Cge
Name:	C-C motif chemokine receptor 10; targeted mutation 1, Craig Gerard
MGI ID:	MGI:3036706
Synonyms:	CCR10 -
Gene:	Ccr10  Location: Chr11:101063824-101066269 bp, - strand  Genetic Position: Chr11, 64.34 cM
Alliance:	Ccr10tm1Cge page

Germline Transmission:	Earliest citation of germline transmission: J:69621
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: The first ATG codon of the gene was mutated to an EcoRV site, with an enhanced GFP gene and a neomycin resistance cassette being inserted into the EcoRV site. Gene inactivation was confirmed by a lack of product from RT-PCR of Peyer's patch RNA. GFP expression was observed in B cells expressing IgA, and in other leukocyte subsets including neutrophils. (J:69621, J:140728)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ccr10 Mutation:	13 strains or lines available

Original:	J:69621 Bhat MA, et al., Axon-glia interactions and the domain organization of myelinated axons requires neurexin iv/caspr/paranodin. Neuron. 2001 May;30(2):369-83
All:	7 reference(s)