Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ntsr1tm1Hmno
Name:	neurotensin receptor 1; targeted mutation 1, Hiroshi Maeno
MGI ID:	MGI:3029204
Gene:	Ntsr1  Location: Chr2:180141769-180186772 bp, + strand  Genetic Position: Chr2, 103.04 cM, cytoband H1-H4
Alliance:	Ntsr1tm1Hmno page

Germline Transmission:	Earliest citation of germline transmission: J:87872
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2, which encodes the fifth and sixth transmembrane domains, was replaced with a neomycin selection cassette inserted by homologous recombination. Transcript was undetected by RT-PCR analysis. (J:87872)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ntsr1 Mutation:	31 strains or lines available

Original:	J:87872 Maeno H, et al., Comparison of mice deficient in the high- or low-affinity neurotensin receptors, Ntsr1 or Ntsr2, reveals a novel function for Ntsr2 in thermal nociception. Brain Res. 2004 Feb 13;998(1):122-9
All:	5 reference(s)