Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Myod1tm1.1Glh
Name:	myogenic differentiation 1; targeted mutation 1.1, David J Goldhamer
MGI ID:	MGI:3027189
Synonyms:	CEloxP
Gene:	Myod1  Location: Chr7:46025898-46028516 bp, + strand  Genetic Position: Chr7, 30.03 cM
Alliance:	Myod1tm1.1Glh page

Germline Transmission:	Earliest citation of germline transmission: J:87370
Parent Cell Line:	GS1 (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Modified regulatory region, Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The floxed neo cassette was excised from Myod1tm1Glh via cre-mediated recombination, leaving a single loxP site in place of the core enhancer. Northern blot analysis indicated that the transcript level was approximately 70% of that observerd in wild-type mice. (J:87370)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

46 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myod1 Mutation:	23 strains or lines available

Original:	J:87370 Chen JC, et al., The core enhancer is essential for proper timing of MyoD activation in limb buds and branchial arches. Dev Biol. 2004 Jan 15;265(2):502-12
All:	4 reference(s)