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Zbtb2 Gene Detail
Summary
  • Symbol
    Zbtb2
  • Name
    zinc finger and BTB domain containing 2
  • Synonyms
    LOC381990
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685949
    NCBI Gene: 381990
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:4317075-4338108 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 2.06 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    71 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685949
 protein coding gene Chr10:4317074-4353114 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016977
 protein coding gene Chr10:1355013-1378725 (-)
A/J MGP_AJ_G0016955
 protein coding gene Chr10:1288191-1309878 (-)
AKR/J MGP_AKRJ_G0016920
 protein coding gene Chr10:1280030-1301920 (-)
BALB/cJ MGP_BALBcJ_G0016913
 protein coding gene Chr10:1259108-1281048 (-)
C3H/HeJ MGP_C3HHeJ_G0016738
 protein coding gene Chr10:1373391-1395058 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017376
 protein coding gene Chr10:1382882-1411030 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015082
 protein coding gene Chr10:1115643-1135710 (-)
CAST/EiJ MGP_CASTEiJ_G0016320
 protein coding gene Chr10:1410230-1431281 (-)
CBA/J MGP_CBAJ_G0016710
 protein coding gene Chr10:1409735-1460019 (-)
DBA/2J MGP_DBA2J_G0016818
 protein coding gene Chr10:1291725-1311751 (-)
FVB/NJ MGP_FVBNJ_G0016813
 protein coding gene Chr10:1249667-1271588 (-)
LP/J MGP_LPJ_G0016893
 protein coding gene Chr10:1356116-1378583 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016844
 protein coding gene Chr10:1350496-1371336 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017413
 protein coding gene Chr10:1297170-1319400 (-)
PWK/PhJ MGP_PWKPhJ_G0016106
 protein coding gene Chr10:1289991-1312700 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015887
 protein coding gene Chr10:1468685-1492190 (-)
WSB/EiJ MGP_WSBEiJ_G0016381
 protein coding gene Chr10:1357274-1380222 (-)



Homology
more
  • Human Ortholog
    ZBTB2, zinc finger and BTB domain containing 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZBTB2, zinc finger and BTB domain containing 2
  • Synonyms
    ZNF437
  • Links
    NCBI Gene ID: 57621
    neXtProt AC: NX_Q8N680
    UniProt: Q8N680

  • Chr Location
    6q25.1; chr6:151364115-151391559 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    53
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075327 Ensembl Gene Model | MGI Sequence Detail 21034 C57BL/6J ±  kb
transcript ENSMUST00000100077 Ensembl | MGI Sequence Detail 3086 Not Applicable  
polypeptide ENSMUSP00000097655 Ensembl | MGI Sequence Detail 514 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 54
    cDNA 53
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:308922 Medeiros de Araujo JA, et al., ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex. Development. 2021 Aug 15;148(16):dev196642
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory