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Mettl21e Gene Detail
Summary
  • Symbol
    Mettl21e
  • Name
    methyltransferase like 21E
  • Synonyms
    4832428D23Rik, LOC381340
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685837
    NCBI Gene: 403183
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:44243230-44258121 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 23.63 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    315 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685837
 protein coding gene Chr1:44238651-44258260 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015990
 protein coding gene Chr1:43246530-43261638 (-)
A/J MGP_AJ_G0015974
 protein coding gene Chr1:41914320-41929262 (-)
AKR/J MGP_AKRJ_G0015929
 protein coding gene Chr1:42487213-42502420 (-)
BALB/cJ MGP_BALBcJ_G0015928
 protein coding gene Chr1:41591045-41605921 (-)
C3H/HeJ MGP_C3HHeJ_G0015761
 protein coding gene Chr1:42878948-42900530 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016381
 protein coding gene Chr1:44982054-44996962 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014103
 protein coding gene Chr1:38745254-38762400 (-)
CAST/EiJ MGP_CASTEiJ_G0015342
 protein coding gene Chr1:42894963-42910698 (-)
CBA/J MGP_CBAJ_G0015733
 protein coding gene Chr1:46302406-46320897 (-)
DBA/2J MGP_DBA2J_G0015834
 protein coding gene Chr1:41214994-41229697 (-)
FVB/NJ MGP_FVBNJ_G0015836
 protein coding gene Chr1:40710608-40725723 (-)
LP/J MGP_LPJ_G0015904
 protein coding gene Chr1:43572877-43587728 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015856
 protein coding gene Chr1:48272308-48302846 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016428
 protein coding gene Chr1:42708468-42723326 (-)
PWK/PhJ MGP_PWKPhJ_G0015125
 protein coding gene Chr1:41091292-41107138 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014907
 protein coding gene Chr1:42733749-42751561 (-)
WSB/EiJ MGP_WSBEiJ_G0015404
 protein coding gene Chr1:42752596-42768384 (-)



Homology
more
  • Human Ortholog
    METTL21EP, methyltransferase like 21E, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    METTL21EP, methyltransferase like 21E, pseudogene
  • Synonyms
    METTL21CP1
  • Links
    NCBI Gene ID: 121952
    UniProt: A6NDL7

  • Chr Location
    13q33.1; chr13:102880040-102896033 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • cDNA Data
    9
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046828 Ensembl Gene Model | MGI Sequence Detail 14892 C57BL/6J ±  kb
transcript ENSMUST00000054801 Ensembl | MGI Sequence Detail 3211 Not Applicable  
polypeptide ENSMUSP00000056481 Ensembl | MGI Sequence Detail 244 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • EC
    2.1.1.-
  • InterPro Domains
    IPR019410 Lysine methyltransferase
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory