About   Help   FAQ
Cd300lb Gene Detail
Summary
  • Symbol
    Cd300lb
  • Name
    CD300 molecule like family member B
  • Synonyms
    Clm7, CLM-7, LMIR5, LOC217304
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685099
    NCBI Gene: 217304
  • Alliance
    gene page
  • Transcription Start Sites
    19 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:114813605-114825197 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 80.55 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    101 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685099
 protein coding gene Chr11:114813605-114825212 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019364
 protein coding gene Chr11:118889468-118904689 (-)
A/J MGP_AJ_G0019333
 protein coding gene Chr11:113713200-113724870 (-)
AKR/J MGP_AKRJ_G0019301
 protein coding gene Chr11:117091047-117102604 (-)
BALB/cJ MGP_BALBcJ_G0019306
 protein coding gene Chr11:114121298-114132842 (-)
C3H/HeJ MGP_C3HHeJ_G0019115
 protein coding gene Chr11:117427968-117439371 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019757
 protein coding gene Chr11:122451514-122465310 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017381
 protein coding gene Chr11:110792688-110804126 (-)
CAST/EiJ MGP_CASTEiJ_G0018669
 protein coding gene Chr11:118765068-118779074 (-)
CBA/J MGP_CBAJ_G0019085
 protein coding gene Chr11:127359509-127371273 (-)
DBA/2J MGP_DBA2J_G0019197
 protein coding gene Chr11:113150179-113162187 (-)
FVB/NJ MGP_FVBNJ_G0019188
 protein coding gene Chr11:112631326-112642891 (-)
LP/J MGP_LPJ_G0019267
 protein coding gene Chr11:119288664-119301233 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019219
 protein coding gene Chr11:126495395-126507040 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019794
 protein coding gene Chr11:117750928-117764100 (-)
PWK/PhJ MGP_PWKPhJ_G0018434
 protein coding gene Chr11:114386706-114398355 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018226
 protein coding gene Chr11:117559084-117576758 (-)
WSB/EiJ MGP_WSBEiJ_G0018721
 protein coding gene Chr11:117709294-117721804 (-)



Homology
more
  • Human Ortholog
    CD300LB, CD300 molecule like family member b
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CD300LB, CD300 molecule like family member b
  • Synonyms
    CD300b, CLM7, CLM-7, CMRF35-A2, IREM3, IREM-3, TREM5, TREM-5
  • Links
    NCBI Gene ID: 124599
    neXtProt AC: NX_A8K4G0
    UniProt: A8K4G0

  • Chr Location
    17q25.1; chr17:74521174-74531475 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 images
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation do not display any gross abnormalities and are protected from ischemia reperfusion induced renal injury.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 217304 NCBI Gene Model | MGI Sequence Detail 11593 C57BL/6J ±  kb
transcript NM_199221 RefSeq | MGI Sequence Detail 2867 C57BL/6  
polypeptide Q3U497 UniProt | EBI | MGI Sequence Detail 209 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 2
References
more
  • Summaries
    All 34
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:86931 Chung DH, et al., CMRF-35-like molecule-1, a novel mouse myeloid receptor, can inhibit osteoclast formation. J Immunol. 2003 Dec 15;171(12):6541-8
  • Latest
    J:334747 Avlas S, et al., CD300b regulates intestinal inflammation and promotes repair in colitis. Front Immunol. 2023;14:1050245
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory