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Banf2 Gene Detail
Summary
  • Symbol
    Banf2
  • Name
    BANF family member 2
  • Synonyms
    4930517K23Rik, barrier to autointegration factor 2, LOC228710
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684961
    NCBI Gene: 403171
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:143875022-143915899 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 70.91 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    493 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684961
protein coding gene Chr2:143874979-143915899 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026580
protein coding gene Chr2:148090133-148135546 (+)
A/J MGP_AJ_G0026544
protein coding gene Chr2:142106297-142147937 (+)
AKR/J MGP_AKRJ_G0026518
protein coding gene Chr2:146187596-146231370 (+)
BALB/cJ MGP_BALBcJ_G0026556
protein coding gene Chr2:142555009-142596738 (+)
C3H/HeJ MGP_C3HHeJ_G0026299
protein coding gene Chr2:146728117-146769541 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027001
protein coding gene Chr2:152557935-152604591 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024378
protein coding gene Chr2:136297447-136335784 (+)
CAST/EiJ MGP_CASTEiJ_G0025760
protein coding gene Chr2:147056244-147102476 (+)
CBA/J MGP_CBAJ_G0026279
protein coding gene Chr2:158095683-158142329 (+)
DBA/2J MGP_DBA2J_G0026413
protein coding gene Chr2:141399321-141442069 (+)
FVB/NJ MGP_FVBNJ_G0026377
protein coding gene Chr2:139986937-140027462 (+)
LP/J MGP_LPJ_G0026517
protein coding gene Chr2:148263274-148307952 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026397
protein coding gene Chr2:162323547-162367443 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027056
protein coding gene Chr2:146192029-146233632 (+)
PWK/PhJ MGP_PWKPhJ_G0025496
protein coding gene Chr2:141052175-141095094 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025297
protein coding gene Chr2:145230919-145273856 (+)
WSB/EiJ MGP_WSBEiJ_G0025833
protein coding gene Chr2:147198836-147247083 (+)



Homology
more
  • Human Ortholog
    BANF2, BANF family member 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BANF2, BANF family member 2
  • Synonyms
    BAF2, BAFL, BAF-L, C20orf179
  • Links
    NCBI Gene ID: 140836
    neXtProt AC: NX_Q9H503
    UniProt: Q9H503

  • Chr Location
    20p12.1; chr20:17693672-17735871 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    4
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Banf2
  • Find Mice (IMSR)
Male mice homozygous for a null allele exhibit normal fecundity.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 403171 NCBI Gene Model | MGI Sequence Detail 40878 C57BL/6J ±  kb
transcript NM_207275 RefSeq | MGI Sequence Detail 526 C57BL/6  
polypeptide Q8BVR0 UniProt | EBI | MGI Sequence Detail 90 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000004638 barrier-to-autointegration factor-like protein
  • InterPro Domains
    IPR004122 Barrier- to-autointegration factor, BAF
    IPR036617 Barrier-to-autointegration factor, BAF superfamily
Molecular
Reagents
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  • All nucleic 15
    cDNA 12
    Primer pair 3

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:321603 Huang C, et al., BAF-L Modulates Histone-to-Protamine Transition during Spermiogenesis. Int J Mol Sci. 2022 Feb 11;23(4)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory