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Togaram1 Gene Detail
Summary
  • Symbol
    Togaram1
  • Name
    TOG array regulator of axonemal microtubules 1
  • Synonyms
    A430041B07Rik, Fam179b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684313
    NCBI Gene: 328108
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:65012578-65069347 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 12, 27.21 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    185 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684313
protein coding gene Chr12:65012350-65069347 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019777
protein coding gene Chr12:64441899-64506409 (+)
A/J MGP_AJ_G0019736
protein coding gene Chr12:62065311-62126988 (+)
AKR/J MGP_AKRJ_G0019711
protein coding gene Chr12:64038110-64099457 (+)
BALB/cJ MGP_BALBcJ_G0019716
protein coding gene Chr12:62511238-62569121 (+)
C3H/HeJ MGP_C3HHeJ_G0019521
protein coding gene Chr12:64387746-64447357 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020168
protein coding gene Chr12:66481226-66541791 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017788
protein coding gene Chr12:59883246-59943179 (+)
CAST/EiJ MGP_CASTEiJ_G0019073
protein coding gene Chr12:59089538-59150522 (+)
CBA/J MGP_CBAJ_G0019490
protein coding gene Chr12:68903961-68969948 (+)
DBA/2J MGP_DBA2J_G0019606
protein coding gene Chr12:61993156-62051195 (+)
FVB/NJ MGP_FVBNJ_G0019594
protein coding gene Chr12:61019779-61081764 (+)
LP/J MGP_LPJ_G0019678
protein coding gene Chr12:64462434-64527734 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019632
protein coding gene Chr12:71756260-71832549 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020202
protein coding gene Chr12:63435763-63493932 (+)
PWK/PhJ MGP_PWKPhJ_G0018839
protein coding gene Chr12:56269202-56328345 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018633
protein coding gene Chr12:57754580-57815570 (+)
WSB/EiJ MGP_WSBEiJ_G0019124
protein coding gene Chr12:63959647-64021549 (+)



Homology
more
  • Human Ortholog
    TOGARAM1, TOG array regulator of axonemal microtubules 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TOGARAM1, TOG array regulator of axonemal microtubules 1
  • Synonyms
    FAM179B, JBTS37, KIAA0423
  • Links
    NCBI Gene ID: 23116
    neXtProt AC: NX_Q9Y4F4
    UniProt: Q9Y4F4

  • Chr Location
    14q21.2; chr14:44962190-45074431 (+)  GRCh38

Human Diseases
more
  • Diseases
    1 with human TOGARAM1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000035614 Ensembl Gene Model | MGI Sequence Detail 56770 C57BL/6J ±  kb
    transcript ENSMUST00000223166 Ensembl | MGI Sequence Detail 6386 Not Applicable  
    polypeptide ENSMUSP00000152616 Ensembl | MGI Sequence Detail 1826 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:3039581
    References
    more
    • Summaries
      All 33
      Gene Ontology 4
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:238707 Maggipinto MJ, et al., Conditional knockout of TOG results in CNS hypomyelination. Glia. 2017 Mar;65(3):489-501

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/19/2024
    MGI 6.23
    The Jackson Laboratory