Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mogtm1Reid
Name:	myelin oligodendrocyte glycoprotein; targeted mutation 1, Hugh H Reid
MGI ID:	MGI:2683672
Synonyms:	MOG-
Gene:	Mog  Location: Chr17:37321635-37334290 bp, - strand  Genetic Position: Chr17, 19.16 cM, cytoband C
Alliance:	Mogtm1Reid page

Germline Transmission:	Earliest citation of germline transmission: J:86663
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 1.4 kb genomic fragment, containing the proximal promoter and exon 1, was replaced with a neomycin selection cassette. Protein was undetected by Western blot analysis of homozygous mutant CNS tissue. (J:86663)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mog Mutation:	58 strains or lines available

Original:	J:86663 Linares D, et al., The magnitude and encephalogenic potential of autoimmune response to MOG is enhanced in MOG deficient mice. J Autoimmun. 2003 Dec;21(4):339-51
All:	4 reference(s)