Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol: Id1tm1Zhu Name: inhibitor of DNA binding 1, HLH protein; targeted mutation 1, Yuan Zhuang MGI ID: MGI:2679939 Synonyms: Id1- Gene: Id1  Location: Chr2:152578171-152579330 bp, + strand  Genetic Position: Chr2, 75.41 cM Alliance: Id1tm1Zhu page

Osteoporotic phenotype of 6 week old Id1tm1Zhu/Id1tm1Zhu mice Show the 3 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:44278
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: All of exon 1 and part of the promoter sequence were replaced with a PGK neomycin resistance cassette. Disruption was confirmed by Northern blot analysis. (J:44278)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Id1 Mutation:	8 strains or lines available

Original:	J:44278 Yan W, et al., High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice. Mol Cell Biol. 1997 Dec;17(12):7317-27
All:	36 reference(s)