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Skic3 Gene Detail
Summary
  • Symbol
    Skic3
  • Name
    SKI3 subunit of superkiller complex
  • Synonyms
    mKIAA0372, Ttc37
  • Feature Type
    protein coding gene
  • IDs
    MGI:2679923
    NCBI Gene: 218343
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:76246853-76338435 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 40.95 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    993 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2679923
 protein coding gene Chr13:76246837-76338437 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020778
 protein coding gene Chr13:76642327-76736114 (+)
A/J MGP_AJ_G0020734
 protein coding gene Chr13:74033756-74125743 (+)
AKR/J MGP_AKRJ_G0020707
 protein coding gene Chr13:76277421-76366274 (+)
BALB/cJ MGP_BALBcJ_G0020730
 protein coding gene Chr13:74518441-74606624 (+)
C3H/HeJ MGP_C3HHeJ_G0020524
 protein coding gene Chr13:75985393-76080604 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021167
 protein coding gene Chr13:79217727-79312042 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018735
 protein coding gene Chr13:70840967-70930822 (+)
CAST/EiJ MGP_CASTEiJ_G0020042
 protein coding gene Chr13:75063561-75155724 (+)
CBA/J MGP_CBAJ_G0020483
 protein coding gene Chr13:82225148-82324480 (+)
DBA/2J MGP_DBA2J_G0020608
 protein coding gene Chr13:73739538-73830623 (+)
FVB/NJ MGP_FVBNJ_G0020588
 protein coding gene Chr13:72799532-72885539 (+)
LP/J MGP_LPJ_G0020681
 protein coding gene Chr13:76918443-77002094 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020617
 protein coding gene Chr13:80622148-80724262 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021207
 protein coding gene Chr13:75603600-75697116 (+)
PWK/PhJ MGP_PWKPhJ_G0019795
 protein coding gene Chr13:72653048-72743062 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019618
 protein coding gene Chr13:71969757-72063334 (+)
WSB/EiJ MGP_WSBEiJ_G0020099
 protein coding gene Chr13:76099941-76206322 (+)



Homology
more
  • Human Ortholog
    SKIC3, SKI3 subunit of superkiller complex
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SKIC3, SKI3 subunit of superkiller complex
  • Synonyms
    KIAA0372, Ski3, THES, TTC37
  • Links
    NCBI Gene ID: 9652
    neXtProt AC: NX_Q6PGP7
    UniProt: Q6PGP7

  • Chr Location
    5q15; chr5:95461755-95555050 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SKIC3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    70
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000033991 Ensembl Gene Model | MGI Sequence Detail 91583 C57BL/6J ±  kb
    transcript ENSMUST00000224386 Ensembl | MGI Sequence Detail 6976 Not Applicable  
    polypeptide ENSMUSP00000153521 Ensembl | MGI Sequence Detail 1563 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 71
      cDNA 71

      Microarray probesets 4
    References
    more
    • Summaries
      All 37
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory