Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Arnttm1.2Gonz
Name:	aryl hydrocarbon receptor nuclear translocator; targeted mutation 1.2, Frank Gonzalez
MGI ID:	MGI:2679362
Synonyms:	Arntdelta
Gene:	Arnt  Location: Chr3:95341699-95404551 bp, + strand  Genetic Position: Chr3, 40.74 cM
Alliance:	Arnttm1.2Gonz page

Germline Transmission:	Earliest citation of germline transmission: J:85934
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A single loxP site remained in place of exon 6 after the floxed region encompassing a neo cassette and exon 6 was excised from Arnttm1Gonz via cre mediated recombination in the germline. (J:85934)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arnt Mutation:	62 strains or lines available

Original:	J:85934 Tomita S, et al., T cell-specific disruption of arylhydrocarbon receptor nuclear translocator (Arnt) gene causes resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced thymic involution. J Immunol. 2003 Oct 15;171(8):4113-20
All:	3 reference(s)