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Traf6tm1Ywc
Targeted Allele Detail
Summary
Symbol: Traf6tm1Ywc
Name: TNF receptor-associated factor 6; targeted mutation 1, Yongwon Choi
MGI ID: MGI:2678775
Synonyms: TRAF6-, Traf6-deltaT
Gene: Traf6  Location: Chr2:101508774-101532014 bp, + strand  Genetic Position: Chr2, 53.9 cM
Alliance: Traf6tm1Ywc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:85808
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 7, which encodes the last zinc finger domain and the entire TRAF domain, was deleted via cre-mediated recombination prior to germline transmission. (J:85808)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Traf6 Mutation:  31 strains or lines available
References
Original:  J:85808 Kobayashi T, et al., TRAF6 is a critical factor for dendritic cell maturation and development. Immunity. 2003 Sep;19(3):353-63
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory