Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rapgef1tm1Mats
Name:	Rap guanine nucleotide exchange factor (GEF) 1; targeted mutation 1, Michiyuki Matsuda
MGI ID:	MGI:2675465
Synonyms:	C3G-
Gene:	Rapgef1  Location: Chr2:29509732-29630376 bp, + strand  Genetic Position: Chr2, 20.32 cM, cytoband B
Alliance:	Rapgef1tm1Mats page

Germline Transmission:	Earliest citation of germline transmission: J:77323
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 15 and 16 were replaced with a neomycin selection cassette inserted by homologous recombination. (J:77323)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rapgef1 Mutation:	192 strains or lines available

Original:	J:77323 Ohba Y, et al., Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis. EMBO J. 2001 Jul 2;20(13):3333-41
All:	1 reference(s)