Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kcnc3tm1Echa
Name:	potassium voltage gated channel, Shaw-related subfamily, member 3; targeted mutation 1, Emily Chan
MGI ID:	MGI:2675309
Synonyms:	Kv3.3-
Gene:	Kcnc3  Location: Chr7:44240088-44254178 bp, + strand  Genetic Position: Chr7, 28.85 cM
Alliance:	Kcnc3tm1Echa page

Germline Transmission:	Earliest citation of germline transmission: J:71179
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The endogenous locus was disrupted by a PGK-neo cassette inserted by homologous recombination. The deleted region included the start codon. Protein was undetected by Western blot analysis of homozygous mutant mice. (J:71179)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnc3 Mutation:	28 strains or lines available

Original:	J:71179 Espinosa F, et al., Alcohol hypersensitivity, increased locomotion, and spontaneous myoclonus in mice lacking the potassium channels Kv3.1 and Kv3.3. J Neurosci. 2001 Sep 1;21(17):6657-65
All:	14 reference(s)