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Meox2tm1Vpa
Targeted Allele Detail
Summary
Symbol: Meox2tm1Vpa
Name: mesenchyme homeobox 2; targeted mutation 1, Vassilis Pachnis
MGI ID: MGI:2674242
Synonyms: Meox2tm1Pach, Mox2-
Gene: Meox2  Location: Chr12:37158539-37229533 bp, + strand  Genetic Position: Chr12, 16.84 cM
Alliance: Meox2tm1Vpa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:56172
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette inserted by homologous recombination replaced exon 1. Transcript was undetected by Northern blot analysis of RNA obtained from homozygous mutant heart, kidney, lung, and liver tissue. (J:56172)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 assay results
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Meox2 Mutation:  18 strains or lines available
References
Original:  J:56172 Mankoo BS, et al., Mox2 is a component of the genetic hierarchy controlling limb muscle development. Nature. 1999 Jul 1;400(6739):69-73
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory