About   Help   FAQ
Gnpattm1Just
Targeted Allele Detail
Summary
Symbol: Gnpattm1Just
Name: glyceronephosphate O-acyltransferase; targeted mutation 1, Wilhelm W Just
MGI ID: MGI:2670461
Synonyms: DAPAT-
Gene: Gnpat  Location: Chr8:125589772-125616796 bp, + strand  Genetic Position: Chr8, 72.81 cM
Alliance: Gnpattm1Just page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:84690
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 5 through 7 were replaced by a neomycin selection cassette. Protein was undetected by Western blot analysis of protein extracts obtained from the Harderian glands of homozygous mutant mice. (J:84690)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 14 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gnpat Mutation:  41 strains or lines available
References
Original:  J:84690 Rodemer C, et al., Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice. Hum Mol Genet. 2003 Aug 1;12(15):1881-95
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory