Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ifnar1tm1Pjh
Name:	interferon (alpha and beta) receptor 1; targeted mutation 1, Paul J Hertzog
MGI ID:	MGI:2667975
Synonyms:	IFNAR1 -
Gene:	Ifnar1  Location: Chr16:91282126-91304329 bp, + strand  Genetic Position: Chr16, 52.98 cM
Alliance:	Ifnar1tm1Pjh page

Germline Transmission:	Earliest citation of germline transmission: J:36004
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: The endogenous locus was disrupted by the insertion of a neo cassette into exon 5. Transcript was undetected by RT-PCR analysis of homozygous mutant mice. (J:36004)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ifnar1 Mutation:	59 strains or lines available

Original:	J:36004 Hwang SY, et al., A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons alpha and beta and alters macrophage responses. Proc Natl Acad Sci U S A. 1995 Nov 21;92(24):11284-8
All:	50 reference(s)