Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Mgat2tm1.1Jxm
Name:	mannoside acetylglucosaminyltransferase 2; targeted mutation 1.1, Jamey Marth
MGI ID:	MGI:2667740
Synonyms:	Mgat2delta
Gene:	Mgat2  Location: Chr12:69230931-69233544 bp, + strand  Genetic Position: Chr12, 28.73 cM
Alliance:	Mgat2tm1.1Jxm page

Germline Transmission:	Earliest citation of germline transmission: J:80661
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region, which is contained within a single exon, was deleted when the flanking loxP sites present in Mgat2tm1Jxm were recombined in the germline. (J:80661)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

13 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mgat2 Mutation:	16 strains or lines available

Original:	J:80661 Wang Y, et al., Modeling human congenital disorder of glycosylation type IIa in the mouse: conservation of asparagine-linked glycan-dependent functions in mammalian physiology and insights into disease pathogenesis. Glycobiology. 2001 Dec;11(12):1051-70
All:	3 reference(s)