Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dclre1ctm1.1Fwa
Name:	DNA cross-link repair 1C; targeted mutation 1.1, Frederick W Alt
MGI ID:	MGI:2667616
Synonyms:	ArtL
Gene:	Dclre1c  Location: Chr2:3425168-3465167 bp, + strand  Genetic Position: Chr2, 1.93 cM
Alliance:	Dclre1ctm1.1Fwa page

Germline Transmission:	Earliest citation of germline transmission: J:80995
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: A single loxP site was left in place of exons 5 and 6 after the floxed neo cassette was removed from Dclre1ctm1Fwa ES cells via cre-mediated recombination. (J:80995)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dclre1c Mutation:	30 strains or lines available

Original:	J:80995 Rooney S, et al., Leaky scid phenotype associated with defective v(d)j coding end processing in artemis-deficient mice. Mol Cell. 2002 Dec;10(6):1379-90
All:	9 reference(s)