Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Blnktm1Dkit
Name:	B cell linker; targeted mutation 1, Daisuke Kitamura
MGI ID:	MGI:2665856
Synonyms:	BASH-
Gene:	Blnk  Location: Chr19:40917371-40982664 bp, - strand  Genetic Position: Chr19, 34.26 cM
Alliance:	Blnktm1Dkit page

Germline Transmission:	Earliest citation of germline transmission: J:84040
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: The endogenous locus was disrupted by a polyadenylation signal inserted by homologous recombination. Neither transcript nor protein was detected by Northern and Western blot analyses of homozygous mutant splenic cells. Germline transmission of the allele generated in J:80920 was achieved in J:85014. (J:80920, J:84040)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Blnk Mutation:	76 strains or lines available

Original:	J:84040 Hayashi K, et al., Distinct signaling requirements for Dmu selection, IgH allelic exclusion, pre-B cell transition, and tumor suppression in B cell progenitors. Immunity. 2003 Jun;18(6):825-36
All:	9 reference(s)