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Hint1tm1.1Tpm
Targeted Allele Detail
Summary
Symbol: Hint1tm1.1Tpm
Name: histidine triad nucleotide binding protein 1; targeted mutation 1.1, Tomi P Makela
MGI ID: MGI:2663678
Synonyms: Hint-
Gene: Hint1  Location: Chr11:54757209-54761327 bp, + strand  Genetic Position: Chr11, 32.13 cM
Alliance: Hint1tm1.1Tpm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:83562
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele is derived from Hinttm1Tpm by crossing mutant animals to cre deleter strain Tg(Pgk1-cre)1Lni. Exons 2 and 3 were deleted by homologous recombination between flanking loxP sites. A single loxP site and a PGK-neo cassette remains in the place of exon 2 and exon 3. (J:83562)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hint1 Mutation:  24 strains or lines available
References
Original:  J:83562 Korsisaari N, et al., The histidine triad protein Hint is not required for murine development or Cdk7 function. Mol Cell Biol. 2003 Jun;23(11):3929-35
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory