Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dync1h1tm1Noh
Name:	dynein cytoplasmic 1 heavy chain 1; targeted mutation 1, Nobutaka Hirokawa
MGI ID:	MGI:2661091
Synonyms:	cDHC-
Gene:	Dync1h1  Location: Chr12:110567886-110633379 bp, + strand  Genetic Position: Chr12, 60.7 cM
Alliance:	Dync1h1tm1Noh page

Germline Transmission:	Earliest citation of germline transmission: J:78610
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details:  A replacement construct containing a PGK-neo cassette was inserted in the reverse orientation and replaced the second half of the first exon and the first intron of the gene. (J:78610)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dync1h1 Mutation:	194 strains or lines available

Original:	J:78610 Harada A, et al., Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein. J Cell Biol. 1998 Apr 6;141(1):51-9
All:	1 reference(s)