Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ptch1tm2Mps
Name:	patched 1; targeted mutation 2, Matthew P Scott
MGI ID:	MGI:2655210
Synonyms:	ptchD11
Gene:	Ptch1  Location: Chr13:63656142-63721274 bp, - strand  Genetic Position: Chr13, 32.8 cM
Alliance:	Ptch1tm2Mps page

Germline Transmission:	Earliest citation of germline transmission: J:82653
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Hypomorph, Reporter) Mutation:    Insertion   Mutation details: This hypomorphic allele containing lacZ was derived through an aberrant recombination event while generating Ptchtm1Mps. The expression pattern of lacZ matches that of the endogenous gene. (J:82653)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptch1 Mutation:	115 strains or lines available

Original:	J:82653 Oro AE, et al., Hair cycle regulation of Hedgehog signal reception. Dev Biol. 2003 Mar 15;255(2):238-48
All:	6 reference(s)