Cdc42bpg MGI Mouse Gene Detail - MGI:2652845 - CDC42 binding protein kinase gamma

Sequence Map

Chr19:6356486-6375682 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2652845	protein coding gene	Chr19:6356465-6375682 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0024758	protein coding gene	Chr19:3354260-3373455 (+)
A/J	MGP_AJ_G0024724	protein coding gene	Chr19:3171076-3190272 (+)
AKR/J	MGP_AKRJ_G0024697	protein coding gene	Chr19:3264167-3285046 (+)
BALB/cJ	MGP_BALBcJ_G0024724	protein coding gene	Chr19:3169942-3189436 (+)
C3H/HeJ	MGP_C3HHeJ_G0024492	protein coding gene	Chr19:3287275-3306471 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0025170	protein coding gene	Chr19:3409763-3428947 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022604	protein coding gene	Chr19:3092903-3113715 (+)
CAST/EiJ	MGP_CASTEiJ_G0023964	protein coding gene	Chr19:3307178-3327272 (+)
CBA/J	MGP_CBAJ_G0024464	protein coding gene	Chr19:3580430-3599571 (+)
DBA/2J	MGP_DBA2J_G0024591	protein coding gene	Chr19:3159863-3178995 (+)
FVB/NJ	MGP_FVBNJ_G0024557	protein coding gene	Chr19:3174185-3194083 (+)
LP/J	MGP_LPJ_G0024677	protein coding gene	Chr19:3320820-3340095 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024586	protein coding gene	Chr19:3385818-3416314 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025218	protein coding gene	Chr19:3293362-3312772 (+)
PWK/PhJ	MGP_PWKPhJ_G0023710	protein coding gene	Chr19:3189796-3209198 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0023515	protein coding gene	Chr19:3252398-3271585 (+)
WSB/EiJ	MGP_WSBEiJ_G0024026	protein coding gene	Chr19:3305824-3325945 (+)

Vertebrate Orthology Source

Alliance of Genome Resources

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Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

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			Length	Strain/Species	Flank
genomic	ENSMUSG00000024769	Ensembl Gene Model \| MGI Sequence Detail	19197	C57BL/6J	± kb
transcript	ENSMUST00000025681	Ensembl \| MGI Sequence Detail	5995	Not Applicable
polypeptide	ENSMUSP00000025681	Ensembl \| MGI Sequence Detail	1551	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000005207 serine/threonine-protein kinase MRCK gamma

(term hierarchy)
EC

2.7.11.1
InterPro Domains

IPR000961 AGC-kinase, C-terminal

IPR046349 C1-like domain superfamily

IPR001180 Citron homology (CNH) domain

IPR000095 CRIB domain

IPR014930 Myotonic dystrophy protein kinase, coiled coil

IPR011993 PH-like domain superfamily

IPR001849 Pleckstrin homology domain

IPR017441 Protein kinase, ATP binding site

IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain

IPR017892 Protein kinase, C-terminal

IPR000719 Protein kinase domain

IPR011009 Protein kinase-like domain superfamily

IPR008271 Serine/threonine-protein kinase, active site

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Summaries

All 32

Developmental Gene Expression 1

Gene Ontology 5

Phenotypes 4
Earliest

J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
Latest

J:314111 Kwa MQ, et al., MRCKalpha Is Dispensable for Breast Cancer Development in the MMTV-PyMT Model. Cells. 2021 Apr 19;10(4)

TSS for Cdc42bpg:

(View these features in JBrowse)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23