Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Csnk2btm1.2Bb
Name:	casein kinase 2, beta polypeptide; targeted mutation 1.2, Brigitte Boldyreff
MGI ID:	MGI:2450158
Synonyms:	CK2Beta-
Gene:	Csnk2b  Location: Chr17:35335172-35341029 bp, - strand  Genetic Position: Chr17, 18.59 cM
Alliance:	Csnk2btm1.2Bb page

Germline Transmission:	Earliest citation of germline transmission: J:81637
Parent Cell Line:	AT1 (ES Cell)
Strain of Origin:	129S2/SvPasCrl

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: A floxed fragment containing the promoter and exons 1 and 2 was excised via cre-mediated excision. Western blot analysis of heterozygous ES cell extracts indicated that protein was not produced from this allele. (J:81637)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Csnk2b Mutation:	13 strains or lines available

Original:	J:81637 Buchou T, et al., Disruption of the regulatory Beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality. Mol Cell Biol. 2003 Feb;23(3):908-15
All:	2 reference(s)