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H2ac8 Gene Detail
Summary
  • Symbol
    H2ac8
  • Name
    H2A clustered histone 8
  • Synonyms
    Hist1h2ae
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448290
    NCBI Gene: 319166
  • Member of
    Hist1 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23754837-23755394 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 9.80 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    70 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448290
 protein coding gene Chr13:23754691-23755394 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0020252
 protein coding gene Chr13:18611933-18612389 (-)
AKR/J MGP_AKRJ_G0020279
 protein coding gene Chr13:20862915-20863374 (-)
BALB/cJ MGP_BALBcJ_G0020295
 protein coding gene Chr13:20600277-20600736 (-)
C3H/HeJ MGP_C3HHeJ_G0020044
 protein coding gene Chr13:19020065-19020521 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020736
 protein coding gene Chr13:21759369-21772644 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018322
 protein coding gene Chr13:19412012-19412516 (-)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0020180
 protein coding gene Chr13:20153594-20156141 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0020254
 protein coding gene Chr13:21315084-21315375 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0020770
 protein coding gene Chr13:20713957-20714379 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    H2AC16, H2A clustered histone 16
  • Vertebrate Orthologs
    14
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H2AC16, H2A clustered histone 16
  • Synonyms
    dJ193B12.9, H2AC11, H2AC13, H2AC15, H2AC17, H2AFI, H2A/i, H2A.i, HIST1H2AL
  • Links
    NCBI Gene ID: 8332
    neXtProt AC: NX_P0C0S8
    UniProt: P0C0S8

  • Chr Location
    6p22.1; chr6:27865317-27865798 (+)  GRCh38
  • Human Ortholog
    H2AC4, H2A clustered histone 4
  • Synonyms
    H2AC8, H2AFM, H2A/m, HIST1H2AB
  • Links
    NCBI Gene ID: 8335
    neXtProt AC: NX_P04908
    UniProt: P04908

  • Chr Location
    6p22.2; chr6:26033092-26033618 (-)  GRCh38
  • Human Ortholog
    H2AC8, H2A clustered histone 8
  • Synonyms
    H2A.1, H2A.2, H2A/a, H2AC4, H2AFA, HIST1H2AE
  • Links
    NCBI Gene ID: 3012
    neXtProt AC: NX_P04908
    UniProt: P04908

  • Chr Location
    6p22.2; chr6:26216921-26217437 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 319166 NCBI Gene Model | MGI Sequence Detail 558 C57BL/6J ±  kb
    transcript NM_178187 RefSeq | MGI Sequence Detail 558 C57BL/6  
    polypeptide C0HKE4 UniProt | EBI | MGI Sequence Detail 130 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    Molecular
    Reagents
    less
    • All nucleic 11
      Genomic 1
      cDNA 10

      Microarray probesets 3
    References
    more
    • Summaries
      All 28
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:141688 Goldsworthy M, et al., Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance. Diabetes. 2008 Aug;57(8):2234-44
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory