Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tsg101tm1.1Kuw
Name:	tumor susceptibility gene 101; targeted mutation 1.1, Kay-Uwe Wagner
MGI ID:	MGI:2447444
Synonyms:	Tsg101-
Gene:	Tsg101  Location: Chr7:46538697-46569717 bp, - strand  Genetic Position: Chr7, 30.62 cM, cytoband B5
Alliance:	Tsg101tm1.1Kuw page

Germline Transmission:	Earliest citation of germline transmission: J:80891
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: The loxP flanked genomic fragment encompassing the promoter region and exon 1 was excised from tsg101tm1Kuw via cre mediated recombination in the germline. (J:80891)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tsg101 Mutation:	32 strains or lines available

Original:	J:80891 Wagner KU, et al., Tsg101 is essential for cell growth, proliferation, and cell survival of embryonic and adult tissues. Mol Cell Biol. 2003 Jan;23(1):150-62
All:	1 reference(s)