Hoxdtm4.1Ddu
Targeted Allele Detail
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Symbol: |
Hoxdtm4.1Ddu |
Name: |
homeobox D cluster; targeted mutation 4.1, Denis Duboule |
MGI ID: |
MGI:2445975 |
Synonyms: |
HoxDRX, L3 |
Gene: |
Hoxd Location: unknown Genetic Position: Chr2, Syntenic
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Germline Transmission: |
Earliest citation of germline transmission:
J:49264
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Parent Cell Line: |
D3 (ES Cell)
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Strain of Origin: |
129S2/SvPas
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: This allele was generated using the same targeting vector used to generate Hoxdtm4Ddu, which contained a floxed neo cassette followed 303 bp downstream by a 261 bp deletion of region X. The floxed neo cassette was deleted in vitro via cre mediated recombination, leaving a single loxP site and the 261 bp deletion in the intergenic region between Hoxd11 and Hoxd12.
(J:49264)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Hoxd Mutation: |
0 strains or lines available
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Original: |
J:49264 Beckers J, et al., Genetic analysis of a conserved sequence in the HoxD complex: regulatory redundancy or limitations of the transgenic approach?. Dev Dyn. 1998 Sep;213(1):1-11 |
All: |
3 reference(s) |
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