Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pes1tm1Sad
Name:	pescadillo ribosomal biogenesis factor 1; targeted mutation 1, Stephen A Duncan
MGI ID:	MGI:2445464
Synonyms:	pes-
Gene:	Pes1  Location: Chr11:3913975-3930004 bp, + strand  Genetic Position: Chr11, 2.79 cM
Alliance:	Pes1tm1Sad page

Germline Transmission:	Earliest citation of germline transmission: J:80174
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Sequence extending from the 158 3' bases of exon 5 through the first 110 bases of exon 12 was replaced by a PGK-neo cassette inserted by homologous recombination. (J:80174)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pes1 Mutation:	38 strains or lines available

Original:	J:80174 Lerch-Gaggl A, et al., Pescadillo is essential for nucleolar assembly, ribosome biogenesis, and Mammalian cell proliferation. J Biol Chem. 2002 Nov 22;277(47):45347-55
All:	1 reference(s)