Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	St3gal2tm1Jxm
Name:	ST3 beta-galactoside alpha-2,3-sialyltransferase 2; targeted mutation 1, Jamey Marth
MGI ID:	MGI:2445397
Synonyms:	ST3Gal-IIdelta
Gene:	St3gal2  Location: Chr8:111646554-111699112 bp, + strand  Genetic Position: Chr8, 57.81 cM
Alliance:	St3gal2tm1Jxm page

Germline Transmission:	Earliest citation of germline transmission: J:80119
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A single loxP site was left in place of the exon encoding the sialyl motif essential for donor substrate binding and catalytic activity after it was flanked by loxP sites and subsequently excised via in vitro cre mediated recombination. (J:80119)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any St3gal2 Mutation:	37 strains or lines available

Original:	J:80119 Ellies LG, et al., Sialyltransferase specificity in selectin ligand formation. Blood. 2002 Nov 15;100(10):3618-25
All:	8 reference(s)