Mst1tm1Jab
Targeted Allele Detail
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| Symbol: |
Mst1tm1Jab |
| Name: |
macrophage stimulating 1 (hepatocyte growth factor-like); targeted mutation 1, Jorge A Bezerra |
| MGI ID: |
MGI:2445230 |
| Synonyms: |
HGFL- |
| Gene: |
Mst1 Location: Chr9:107957635-107962202 bp, + strand Genetic Position: Chr9, 59.07 cM
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| Alliance: |
Mst1tm1Jab page
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Livers of Mst1tm1Jab/Mst1tm1Jab mice display cytoplasmic vacuolization of hepatocytes
Show the 1 phenotype image(s) involving this allele.
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| Germline Transmission: |
Earliest citation of germline transmission:
J:46185
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| Parent Cell Line: |
E14TG2a (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Sequence encompassing a portion of exon 3 and all of exons 4 through 7 was replaced by a PGK-hprt cassette. Endogenous mRNA was undetected by Northern blot analysis of liver tissue obtained from homozygous mutant mice. Western blot analysis of sera indicated an absence of protein.
(J:46185)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Mst1 Mutation: |
39 strains or lines available
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| Original: |
J:46185 Bezerra JA, et al., Biological effects of targeted inactivation of hepatocyte growth factor-like protein in mice. J Clin Invest. 1998 Mar 1;101(5):1175-83 |
| All: |
4 reference(s) |
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Analysis Tools
