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Aasdh Gene Detail
Summary
  • Symbol
    Aasdh
  • Name
    aminoadipate-semialdehyde dehydrogenase
  • Synonyms
    A230062G08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442517
    NCBI Gene: 231326
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:77021506-77053361 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 41.45 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    201 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442517
 protein coding gene Chr5:77021506-77053376 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029648
 protein coding gene Chr5:77084581-77119546 (-)
A/J MGP_AJ_G0029616
 protein coding gene Chr5:74145393-74177613 (-)
AKR/J MGP_AKRJ_G0029564
 protein coding gene Chr5:76562026-76595612 (-)
BALB/cJ MGP_BALBcJ_G0029625
 protein coding gene Chr5:74876322-74909059 (-)
C3H/HeJ MGP_C3HHeJ_G0029348
 protein coding gene Chr5:76934841-76969776 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030079
 protein coding gene Chr5:80160278-80201533 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027320
 protein coding gene Chr5:69775448-69809240 (-)
CAST/EiJ MGP_CASTEiJ_G0028756
 protein coding gene Chr5:76139014-76173642 (-)
CBA/J MGP_CBAJ_G0029317
 protein coding gene Chr5:82813603-82852595 (-)
DBA/2J MGP_DBA2J_G0029462
 protein coding gene Chr5:74203191-74235092 (-)
FVB/NJ MGP_FVBNJ_G0029423
 protein coding gene Chr5:73401678-73433795 (-)
LP/J MGP_LPJ_G0029549
 protein coding gene Chr5:77523256-77560016 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029451
 protein coding gene Chr5:85960414-85992940 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030112
 protein coding gene Chr5:76108567-76142508 (-)
PWK/PhJ MGP_PWKPhJ_G0028479
 protein coding gene Chr5:73219648-73252324 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028314
 protein coding gene Chr5:75470302-75506692 (-)
WSB/EiJ MGP_WSBEiJ_G0028836
 protein coding gene Chr5:76442113-76476679 (-)



Homology
more
  • Human Ortholog
    AASDH, aminoadipate-semialdehyde dehydrogenase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AASDH, aminoadipate-semialdehyde dehydrogenase
  • Synonyms
    ACSF4, LYS2, NRPS1098, NRPS998
  • Links
    NCBI Gene ID: 132949
    neXtProt AC: NX_Q4L235
    UniProt: Q4L235

  • Chr Location
    4q12; chr4:56338287-56387508 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    23
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000055923 Ensembl Gene Model | MGI Sequence Detail 31856 C57BL/6J ±  kb
    transcript ENSMUST00000120963 Ensembl | MGI Sequence Detail 3694 Not Applicable  
    polypeptide ENSMUSP00000113792 Ensembl | MGI Sequence Detail 1100 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 23
      cDNA 23

      Microarray probesets 2
    References
    more
    • Summaries
      All 34
      Gene Ontology 4
      Phenotypes 12
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:233978 Mizuno S, et al., Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation. Sci Rep. 2015;5:13632
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory