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Sh2d7 Gene Detail
Summary
  • Symbol
    Sh2d7
  • Name
    SH2 domain containing 7
  • Synonyms
    4933412E14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441692
    NCBI Gene: 244885
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:54441430-54452304 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 29.70 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    54 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441692
 protein coding gene Chr9:54441407-54452314 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034824
 protein coding gene Chr9:53580308-53586342 (+)
A/J MGP_AJ_G0034805
 protein coding gene Chr9:51876304-51882339 (+)
AKR/J MGP_AKRJ_G0034733
 protein coding gene Chr9:53053845-53059880 (+)
BALB/cJ MGP_BALBcJ_G0034797
 protein coding gene Chr9:51650406-51656441 (+)
C3H/HeJ MGP_C3HHeJ_G0034507
 protein coding gene Chr9:53514209-53520244 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035316
 protein coding gene Chr9:55084428-55090463 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032228
 protein coding gene Chr9:51290784-51296886 (+)
CAST/EiJ MGP_CASTEiJ_G0033829
 protein coding gene Chr9:53526070-53532098 (+)
CBA/J MGP_CBAJ_G0034478
 protein coding gene Chr9:56977574-56983603 (+)
DBA/2J MGP_DBA2J_G0034637
 protein coding gene Chr9:51766055-51772091 (+)
FVB/NJ MGP_FVBNJ_G0034579
 protein coding gene Chr9:50968680-50975635 (+)
LP/J MGP_LPJ_G0034719
 protein coding gene Chr9:53900244-53906278 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034622
 protein coding gene Chr9:58546909-58552944 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035338
 protein coding gene Chr9:53050256-53056842 (+)
PWK/PhJ MGP_PWKPhJ_G0033533
 protein coding gene Chr9:51741957-51748006 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033368
 protein coding gene Chr9:53325762-53331776 (+)
WSB/EiJ MGP_WSBEiJ_G0033941
 protein coding gene Chr9:53028326-53034367 (+)



Homology
more
  • Human Ortholog
    SH2D7, SH2 domain containing 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SH2D7, SH2 domain containing 7
  • Links
    NCBI Gene ID: 646892
    neXtProt AC: NX_A6NKC9
    UniProt: A6NKC9

  • Chr Location
    15q25.1; chr15:78077808-78104370 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    730
  • Tissues
    11
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046460 Ensembl Gene Model | MGI Sequence Detail 10875 C57BL/6J ±  kb
transcript ENSMUST00000118413 Ensembl | MGI Sequence Detail 3045 Not Applicable  
polypeptide ENSMUSP00000113298 Ensembl | MGI Sequence Detail 458 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory