Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Abcd1tm1Ymd
Name:	ATP-binding cassette, sub-family D member 1; targeted mutation 1, Takeshi Yamada
MGI ID:	MGI:2429945
Gene:	Abcd1  Location: ChrX:72760203-72782140 bp, + strand  Genetic Position: ChrX, 37.39 cM, cytoband B
Alliance:	Abcd1tm1Ymd page

Germline Transmission:	Earliest citation of germline transmission: J:40230
Parent Cell Line:	CCE/EK.CCE (ES Cell)
Strain of Origin:	129S/SvEv-Gpi1c

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The 3' portion of exon 1 was replaced with a neomycin selection cassette. The deleted region encoded 284 amino acids. No protein was detected by Western blot analysis of homozygous mutant mice. (J:40230)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Abcd1 Mutation:	14 strains or lines available

Original:	J:40230 Kobayashi T, et al., Adrenoleukodystrophy protein-deficient mice represent abnormality of very long chain fatty acid metabolism. Biochem Biophys Res Commun. 1997 Mar 27;232(3):631-6
All:	3 reference(s)