Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Cd200tm1Jods
Name:	CD200 molecule; targeted mutation 1, Jonathon D Sedgwick
MGI ID:	MGI:2429651
Synonyms:	CD200-
Gene:	Cd200  Location: Chr16:45202498-45229416 bp, - strand  Genetic Position: Chr16, 29.53 cM, cytoband A1
Alliance:	Cd200tm1Jods page

Germline Transmission:	Earliest citation of germline transmission: J:65982
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A portion of exon 3 was replaced by a neomycin selection cassette. Protein expression was examined by immunohistochemical and flow cytometric analyses and determined to be absent in the CNS, B cells, follicular dendritic cells, and splenic endothelium of homozygous mutant mice. (J:65982)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd200 Mutation:	24 strains or lines available

Original:	J:65982 Hoek RM, et al., Down-regulation of the macrophage lineage through interaction with OX2 (CD200). Science. 2000 Dec 1;290(5497):1768-71
All:	21 reference(s)