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Chst10tm1Msch
Targeted Allele Detail
Summary
Symbol: Chst10tm1Msch
Name: carbohydrate sulfotransferase 10; targeted mutation 1, Melitta Schachner
MGI ID: MGI:2388475
Synonyms: ST-
Gene: Chst10  Location: Chr1:38902948-38937242 bp, - strand  Genetic Position: Chr1, 17.24 cM
Alliance: Chst10tm1Msch page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79015
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was replaced with a neomycin selection cassette. Protein product was undetected by Western blot analysis of brain tissue obtained from homozygous mutant mice. (J:79015)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Chst10 Mutation:  22 strains or lines available
References
Original:  J:79015 Senn C, et al., Mice Deficient for the HNK-1 Sulfotransferase Show Alterations in Synaptic Efficacy and Spatial Learning and Memory. Mol Cell Neurosci. 2002 Aug;20(4):712
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory