Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Sall1tm1Ryn
Name:	spalt like transcription factor 1; targeted mutation 1, Ryuichi Nishinakamura
MGI ID:	MGI:2388379
Synonyms:	Sall1-del
Gene:	Sall1  Location: Chr8:89753867-89770790 bp, - strand  Genetic Position: Chr8, 43.51 cM, cytoband D
Alliance:	Sall1tm1Ryn page

Germline Transmission:	Earliest citation of germline transmission: J:71242
Parent Cell Line:	CCE/EK.CCE (ES Cell)
Strain of Origin:	129S/SvEv-Gpi1c

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region, except for sequences encoding the 52 N-terminal amino acids, was deleted and replaced with a neomyin resistance cassette. The mutation removes all zinc finger domains from the gene. Absence of gene expression in homozygous mutant animals was verified by RT-PCR and in situ hybridization. (J:71242)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Sall1 Mutation:	74 strains or lines available

Original:	J:71242 Nishinakamura R, et al., Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development. Development. 2001 Aug;128(16):3105-15
All:	9 reference(s)