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Hoxb4tm2Nrm
Targeted Allele Detail
Summary
Symbol: Hoxb4tm2Nrm
Name: homeobox B4; targeted mutation 2, Nancy R Manley
MGI ID: MGI:2388367
Synonyms: Hoxb4nl
Gene: Hoxb4  Location: Chr11:96209093-96212464 bp, + strand  Genetic Position: Chr11, 59.83 cM
Alliance: Hoxb4tm2Nrm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:71389
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsThe gene was disrupted by insertion of a floxed neomycin resistance cassette in reverse orientation into the first coding exon of the gene. (J:71389)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb4 Mutation:  18 strains or lines available
Notes
ES cell line = R1-45, a subline of R1.
References
Original:  J:71389 Manley NR, et al., Hoxb2 and hoxb4 act together to specify ventral body wall formation. Dev Biol. 2001 Sep 1;237(1):130-44
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory