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Cdkl3 Gene Detail
Summary
  • Symbol
    Cdkl3
  • Name
    cyclin dependent kinase like 3
  • Synonyms
    B230379H01Rik, MGC:28957
  • Feature Type
    protein coding gene
  • IDs
    MGI:2388268
    NCBI Gene: 213084
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:51895048-51980611 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 31.85 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    297 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2388268
protein coding gene Chr11:51891694-51980611 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018280
protein coding gene Chr11:51288485-51385871 (+)
A/J MGP_AJ_G0018249
protein coding gene Chr11:49341909-49430263 (+)
AKR/J MGP_AKRJ_G0018219
protein coding gene Chr11:50895525-50993839 (+)
BALB/cJ MGP_BALBcJ_G0018220
protein coding gene Chr11:49644725-49730297 (+)
C3H/HeJ MGP_C3HHeJ_G0018031
protein coding gene Chr11:50937591-51025734 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018670
protein coding gene Chr11:52823310-52919212 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016322
protein coding gene Chr11:46899317-46980268 (+)
CAST/EiJ MGP_CASTEiJ_G0017596
protein coding gene Chr11:50935115-51028809 (+)
CBA/J MGP_CBAJ_G0018006
protein coding gene Chr11:55324800-55419537 (+)
DBA/2J MGP_DBA2J_G0018113
protein coding gene Chr11:49043057-49137283 (+)
FVB/NJ MGP_FVBNJ_G0018108
protein coding gene Chr11:48770822-48859390 (+)
LP/J MGP_LPJ_G0018189
protein coding gene Chr11:51699244-51795064 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018131
protein coding gene Chr11:56713845-56802474 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018713
protein coding gene Chr11:50998981-51090956 (+)
PWK/PhJ MGP_PWKPhJ_G0017371
protein coding gene Chr11:49581100-49666315 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017166
protein coding gene Chr11:50731788-50823171 (+)
WSB/EiJ MGP_WSBEiJ_G0017643
protein coding gene Chr11:50649327-50735297 (+)



Homology
more
  • Human Ortholog
    CDKL3, cyclin dependent kinase like 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDKL3, cyclin dependent kinase like 3
  • Synonyms
    NKIAMRE
  • Links
    NCBI Gene ID: 51265
    neXtProt AC: NX_Q8IVW4
    UniProt: Q8IVW4

  • Chr Location
    5q31.1; chr5:134283345-134371624 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020389 Ensembl Gene Model | MGI Sequence Detail 85564 C57BL/6J ±  kb
transcript ENSMUST00000120374 Ensembl | MGI Sequence Detail 2770 Not Applicable  
polypeptide ENSMUSP00000113303 Ensembl | MGI Sequence Detail 610 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 26
    Primer pair 4
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2144313, MGI:2444153
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:245730 Bardot P, et al., The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo. Development. 2017 Oct 15;144(20):3808-3818

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory